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Reducing target binding affinity improves the therapeutic index of anti-MET antibody-drug conjugate in tumor bearing animals

Authors :
Amita Datta-Mannan
Hiuwan Choi
Zhaoyan Jin
Ling Liu
Jirong Lu
David J. Stokell
Anthony T. Murphy
Kenneth W. Dunn
Michelle M. Martinez
Yiqing Feng
Source :
PLoS ONE, Vol 19, Iss 4 (2024)
Publication Year :
2024
Publisher :
Public Library of Science (PLoS), 2024.

Subjects

Subjects :
Medicine
Science

Details

Language :
English
ISSN :
19326203
Volume :
19
Issue :
4
Database :
Directory of Open Access Journals
Journal :
PLoS ONE
Publication Type :
Academic Journal
Accession number :
edsdoj.88740c93e82b4e8cb5d7edb2fd408cba
Document Type :
article