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Recent advances in immunotherapy-involved combination cancer therapy based on ZIF-8

Authors :
Guanheng Wang
Lin Li
Jiapeng Wang
Chang Liu
Chunlei Li
Xiuwen Zheng
Source :
AIP Advances, Vol 14, Iss 10, Pp 100704-100704-17 (2024)
Publication Year :
2024
Publisher :
AIP Publishing LLC, 2024.

Abstract

This paper introduces and briefly describes the tumor immune cycle to clarify the action mechanisms and principles of classical immunotherapy. We then focus on the classification of immunotherapies. Immunotherapy strategies can be classified into three categories according to the target of action: immunotherapy based on the regulation of dendritic cells, immunotherapy based on polarized tumor-associated macrophages, and immunotherapy based on the suppression of regulatory T cells. Subsequently, the latest research progress in the use of Zeolitic Imidazolate Framework-8 (ZIF-8) as a vehicle to combine immunotherapy with other therapeutic approaches is examined. Finally, prospects for the application of nanocomposites in combination therapy for tumor immunotherapy are outlined.

Subjects

Subjects :
Physics
QC1-999

Details

Language :
English
ISSN :
21583226
Volume :
14
Issue :
10
Database :
Directory of Open Access Journals
Journal :
AIP Advances
Publication Type :
Academic Journal
Accession number :
edsdoj.88b9b9505774f3e9b4a289a85e2f3cb
Document Type :
article
Full Text :
https://doi.org/10.1063/5.0232660