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Overexpression of annexin 1 in the development and differentiation of urothelial carcinoma

Authors :
Wan-Yi Kang
Wan-Tzu Chen
Ya-Chun Huang
Yue-Chiu Su
Chee-Yin Chai
Source :
Kaohsiung Journal of Medical Sciences, Vol 28, Iss 3, Pp 145-150 (2012)
Publication Year :
2012
Publisher :
Wiley, 2012.

Abstract

This study investigates the expression of annexin 1 in urothelial carcinoma (UC) and its relation with clinicopathologic factors, and evaluates its potential clinical significance. Annexin 1 expression was analyzed by immunohistochemical staining with manual tissue microarrays and Western blot in UC. Immunohistochemical analysis of UC in tissue microarrays showed that annexin 1 protein was 76.5% (150/196) positive, which was markedly increased compared with that in the normal urothelium 20.8% (5/24) (p

Details

Language :
English
ISSN :
1607551X
Volume :
28
Issue :
3
Database :
Directory of Open Access Journals
Journal :
Kaohsiung Journal of Medical Sciences
Publication Type :
Academic Journal
Accession number :
edsdoj.88ea53c1b0b9410488501ea2527e5131
Document Type :
article
Full Text :
https://doi.org/10.1016/j.kjms.2011.10.004