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Self-organization and regulation of intrinsically disordered proteins with folded N-termini.

Authors :
Philip C Simister
Fred Schaper
Nicola O'Reilly
Simon McGowan
Stephan M Feller
Source :
PLoS Biology, Vol 9, Iss 2, p e1000591 (2011)
Publication Year :
2011
Publisher :
Public Library of Science (PLoS), 2011.

Abstract

How do mostly disordered proteins coordinate the specific assembly of very large signal transduction protein complexes? A newly emerging hypothesis may provide some clues towards a molecular mechanism.

Subjects

Subjects :
Biology (General)
QH301-705.5

Details

Language :
English
ISSN :
15449173 and 15457885
Volume :
9
Issue :
2
Database :
Directory of Open Access Journals
Journal :
PLoS Biology
Publication Type :
Academic Journal
Accession number :
edsdoj.8b98bf34c6d345b39e4286426587b0cd
Document Type :
article
Full Text :
https://doi.org/10.1371/journal.pbio.1000591