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Creutzfeldt–Jakob disease: A case report

Authors :
Fahad Rasool Butt, HBSc
Thanansayan Dhivagaran, HBSc
Syed Naqvi, MD, FRCPC, DABR
Source :
Radiology Case Reports, Vol 20, Iss 2, Pp 1095-1098 (2025)
Publication Year :
2025
Publisher :
Elsevier, 2025.

Abstract

Creutzfeldt–Jakob Disease (CJD) is a rare, fatal neurodegenerative disorder that is caused by prion proteins. Patients often present with rapidly progressive dementia, ataxia, myoclonus, memory impairment, visual problems, and changes in personality. In this case report, we aimed to address the course of a 62 year old female who presented with progressive decline in cognitive function and died within 6 months of presentation. The patient underwent cerebrospinal fluid testing, MRI brain, and electroencephalography during her stay in the hospital. Ultimately, an autopsy was performed, which demonstrated spongiform changes, neuronal loss, and astrogliosis, consistent with CJD.

Details

Language :
English
ISSN :
19300433
Volume :
20
Issue :
2
Database :
Directory of Open Access Journals
Journal :
Radiology Case Reports
Publication Type :
Academic Journal
Accession number :
edsdoj.8c4d36ac3e36456d978ef890c2cc26c6
Document Type :
article
Full Text :
https://doi.org/10.1016/j.radcr.2024.11.011