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Enzymatically promoted release of organic molecules linked to magnetic nanoparticles

Authors :
Chiara Lambruschini
Silvia Villa
Luca Banfi
Fabio Canepa
Fabio Morana
Annalisa Relini
Paola Riani
Renata Riva
Fulvio Silvetti
Source :
Beilstein Journal of Nanotechnology, Vol 9, Iss 1, Pp 986-999 (2018)
Publication Year :
2018
Publisher :
Beilstein-Institut, 2018.

Abstract

Magnetite-based magnetic nanoparticles have been successfully coupled to an organic system constituted of a fluorescent molecule, a tripeptide specifier and a spacer. The system is able to selectively release the fluorescent molecule upon targeted enzymatic hydrolysis promoted by a lysine/arginine specific protease.

Details

Language :
English
ISSN :
21904286
Volume :
9
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Beilstein Journal of Nanotechnology
Publication Type :
Academic Journal
Accession number :
edsdoj.8d34493f0af443d29ab99ee4e3b937af
Document Type :
article
Full Text :
https://doi.org/10.3762/bjnano.9.92