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Redβ177 annealase structure reveals details of oligomerization and λ Red-mediated homologous DNA recombination

Authors :
Timothy P. Newing
Jodi L. Brewster
Lucy J. Fitschen
James C. Bouwer
Nikolas P. Johnston
Haibo Yu
Gökhan Tolun
Source :
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

Redβ annealase catalyses single-strand annealing homologous DNA recombination. Here, the authors present a cryo-EM structure of a Redβ annealing intermediate bound to two complementary 27mer oligonucleotides.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
13
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.8eae846edef420e98dca3a781c83034
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-022-33090-6