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Local Electrical Dyssynchrony during Atrial Fibrillation: Theoretical Considerations and Initial Catheter Ablation Results.

Authors :
Pawel Kuklik
Benjamin Schäffer
Boris A Hoffmann
Anand N Ganesan
Doreen Schreiber
Julia M Moser
Ruken Ö Akbulak
Arian Sultan
Daniel Steven
Bart Maesen
Ulrich Schotten
Christian Meyer
Stephan Willems
Source :
PLoS ONE, Vol 11, Iss 10, p e0164236 (2016)
Publication Year :
2016
Publisher :
Public Library of Science (PLoS), 2016.

Abstract

Electrogram-based identification of the regions maintaining persistent Atrial Fibrillation (AF) is a subject of ongoing debate. Here, we explore the concept of local electrical dyssynchrony to identify AF drivers.Local electrical dyssynchrony was calculated using mean phase coherence. High-density epicardial mapping along with mathematical model were used to explore the link between local dyssynchrony and properties of wave conduction. High-density mapping showed a positive correlation between the dyssynchrony and number of fibrillatory waves (R2 = 0.68, p

Subjects

Subjects :
Medicine
Science

Details

Language :
English
ISSN :
19326203
Volume :
11
Issue :
10
Database :
Directory of Open Access Journals
Journal :
PLoS ONE
Publication Type :
Academic Journal
Accession number :
edsdoj.8f79dc679864f7f96d85deb7691ed93
Document Type :
article
Full Text :
https://doi.org/10.1371/journal.pone.0164236