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The Chromenopyridine Scaffold: A Privileged Platform in Drug Design

Authors :
Fábio Pedroso de Lima
Marta Costa
Ana Sousa
Maria Fernanda Proença
Source :
Molecules, Vol 29, Iss 13, p 3004 (2024)
Publication Year :
2024
Publisher :
MDPI AG, 2024.

Abstract

The chromenopyridine scaffold represents an important class of heterocyclic compounds exhibiting a broad spectrum of biological properties. This review describes novel and efficient procedures for the synthesis of this scaffold. Herein, several methods were detailed and grouped according to their starting material (e.g., salicylaldehydes, chromones, chromanones and coumarins) and respective biological activity, when reported. This review highlights the potential of the reported synthetic strategies for preparing chromenopyridine derivatives with promising biological activity, paving the way for further developments in drug discovery.

Details

Language :
English
ISSN :
14203049
Volume :
29
Issue :
13
Database :
Directory of Open Access Journals
Journal :
Molecules
Publication Type :
Academic Journal
Accession number :
edsdoj.90191dbc1a0414a8930942a01271f79
Document Type :
article
Full Text :
https://doi.org/10.3390/molecules29133004