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WBC Count and WBC to Hb Ratio Could Predict Short-Term Recurrence Rate in Multiple Myeloma Patients Underwent Autologous Stem Cell Transplantation

Authors :
Hengameh Mojdeganlou
Ata Abbasi
Rahim Asghari
Source :
Acta Medica Iranica, Vol 61, Iss 4 (2023)
Publication Year :
2023
Publisher :
Tehran University of Medical Sciences, 2023.

Abstract

Multiple myeloma (MM) is a hematologic malignancy with a variable clinical course. We investigated the prognostic role of routine laboratory factors including CBC indices and serum vitamin D levels to predict MM recurrence after receiving an autologous stem cell transplant (ASCT). 29 patients were enrolled. Before ASCT, demographic data and CBC, serum Cr, and Vit D levels were obtained. Patients underwent bone marrow aspiration (BMA) and biopsy (BMB) before ASCT and pretransplant plasma cell counts were also evaluated. Patients were followed for 6 months and BMA and biopsy were done in the 3rd and 6th month of the follow-up to detect recurrence. Overall, 9 patients were reported to have recurrence. The patient's WBC count mean was 13.3±11.6. WBC count was lower in patients with overall recurrence (P=0.005). Patients were divided into 2 groups according to WBC count (

Details

Language :
English
ISSN :
00446025 and 17359694
Volume :
61
Issue :
4
Database :
Directory of Open Access Journals
Journal :
Acta Medica Iranica
Publication Type :
Academic Journal
Accession number :
edsdoj.908f7d54f64d42159ddb1d9cfefe0ee3
Document Type :
article
Full Text :
https://doi.org/10.18502/acta.v61i4.13171