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Genetically encoded protein photocrosslinker with a transferable mass spectrometry-identifiable label
- Source :
- Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
- Publication Year :
- 2016
- Publisher :
- Nature Portfolio, 2016.
-
Abstract
- Mapping protein-protein interaction using crosslinking and mass spectroscopy strategies is hampered by a high rate of false-positive results. Here, the authors develop a genetically encoded photo-affinity probe for accurate identification of protein interaction partners and crosslinking sites.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 7
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.90bd7af9d1c84c018858e3904496dd5c
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/ncomms12299