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Case report: A rare case of malignant solitary fibrous tumor in an adult with an epithelioid pattern in the occipital region

Authors :
Ke Huang
Wen-wen Liu
Xiu-wen Chen
Yin-hua Hao
Sen-yuan Luo
Ling-ling Yuan
Yu-gang Huang
Xian-bin Tang
Source :
Frontiers in Oncology, Vol 14 (2024)
Publication Year :
2024
Publisher :
Frontiers Media S.A., 2024.

Abstract

We illustrated a rare case of malignant solitary fibrous tumor (MSFT) with epithelioid morphology in the occipital region of a 59-year-old female, in which a rare NAB2ex7-STAT6 exon15/16 double fusion subtype was detected by the Next-generation sequencing (NGS) and STAT6 immunohistochemistry (IHC) was diffusely and strongly positively expressed, without recurrence after 20 months of postoperative follow-up. The morphological and molecular genetic aspects and the differential diagnosis are described, and the relevant literature was assessed in order to broaden our understanding and diagnostic capability of this malignancy.

Details

Language :
English
ISSN :
2234943X and 91887895
Volume :
14
Database :
Directory of Open Access Journals
Journal :
Frontiers in Oncology
Publication Type :
Academic Journal
Accession number :
edsdoj.91887895620441f2aa6cea62c94dd299
Document Type :
article
Full Text :
https://doi.org/10.3389/fonc.2024.1339582