Microfluidic-based molecularly imprinted polymers-integrated optic sensors

Molecularly imprinted polymers (MIPs) are cheap and easily prepared polymers that have specific recognition sites for the target molecule that suitable for recognition. MIPs are also synthetic materials designed to mimic the recognition properties of natural antibodies or receptors. The development of MIPs in optic sensors has introduced a significant novelty in the field of sensing technology. When integrated into optic sensors, MIPs offer several advantages and novel capabilities including selective recognition, versatility, stability and reusability, signal amplification, and tailored sensor design. Microfluidic systems are enable the control and movement of fluids in small volumes within micro-scale channels. MIPs, optic sensors and microfluidic systems have important superior features such as sensitivity, selectivity and low sample requirement. They are used together in the creation of fast, automated and self-contained systems. The combination of advantages makes microfluidic-based MIPs-integrated optic sensors a promising technology for various applications in analytical sciences, biomedical research, and environmental monitoring.In this review, we first described molecular imprinting method, molecularly imprinted polymers, microfluidic systems, optic sensors and then mentioned different microfluidic-based molecularly imprinted polymers-integrated optic sensors platform for various molecule detection as applications in several working fields.