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Examination of the Virulence of Actinobacillus pleuropneumoniae Serovar 16 in Pigs

Authors :
Miklós Tenk
Gergely Tóth
Zsuzsanna Márton
Rita Sárközi
Alejandra Szórádi
László Makrai
Nimród Pálmai
Tamás Szalai
Mihály Albert
László Fodor
Source :
Veterinary Sciences, Vol 11, Iss 2, p 62 (2024)
Publication Year :
2024
Publisher :
MDPI AG, 2024.

Abstract

Different virulence variants of A. pleuropneumoniae are involved in the etiology of porcine pleuropneumonia. The purpose of the present trial was examination of the virulence of the Actinobacillus pleuropneumoniae A-85/14 strain, the type strain of serovar 16, in an animal challenge experiment. Thirty 12-week-old piglets seronegative for A. pleuropneumoniae were allocated into three trial groups each of 10 animals, and they were infected intranasally with 106, 107, or 108 colony forming units (cfu) of the strain, respectively. Clinical signs were recorded twice a day, and the animals were euthanized 6 days after the infection. Typical clinical signs and postmortem lesions of porcine pleuropneumonia were seen in the animals of each trial group; however, they were generally mild, and no significant differences could be seen between the three groups. Even 106 colony forming units of A. pleuropneumoniae A-85/14 strain could induce clinical signs and lesions. Based on these results, the type strain of serovar 16 of A. pleuropneumoniae must be regarded as a typical pathogenic strain of the species.

Details

Language :
English
ISSN :
23067381
Volume :
11
Issue :
2
Database :
Directory of Open Access Journals
Journal :
Veterinary Sciences
Publication Type :
Academic Journal
Accession number :
edsdoj.92fe58f0e14064abad4d069a259302
Document Type :
article
Full Text :
https://doi.org/10.3390/vetsci11020062