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Serum vitamin D is substantially reduced and predicts flares in diabetic retinopathy patients

Authors :
Yong Zhuang
Zihao Zhuang
Qingyan Cai
Xin Hu
Huibin Huang
Source :
Journal of Diabetes Investigation, Vol 15, Iss 7, Pp 867-873 (2024)
Publication Year :
2024
Publisher :
Wiley, 2024.

Abstract

ABSTRACT Aims/Introduction Research has suggested that vitamin D deficiency is associated with diabetic retinopathy (DR). Our study aimed to determine whether vitamin D deficiency is the cause of diabetic retinopathy or if diabetic retinopathy reduces vitamin D levels. Materials and Methods Participants with type‐2 diabetes were recruited for this prospective observational clinical study and were divided into a diabetic group without retinopathy and a diabetic group with retinopathy, with additional healthy volunteers serving as a control group. The differences in clinical characteristics among the three groups were also compared. Patients without retinopathy were then followed for 1 year to monitor the incidence of diabetic retinopathy. After follow‐up, participants were divided into subgroups based on whether diabetic retinopathy occurred. The baseline data of the subgroups were compared, and the independent risk factors were analyzed. Results Vitamin D levels were generally low. Participants with diabetic retinopathy had significantly lower vitamin D levels than did those without retinopathy (P

Details

Language :
English
ISSN :
20401124 and 20401116
Volume :
15
Issue :
7
Database :
Directory of Open Access Journals
Journal :
Journal of Diabetes Investigation
Publication Type :
Academic Journal
Accession number :
edsdoj.930b7d8be13437c8437342ebc1d81e2
Document Type :
article
Full Text :
https://doi.org/10.1111/jdi.14185