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Genetic Predisposition to Neurological Complications in Patients with COVID-19

Authors :
Nikhil Shri Sahajpal
Alex R. Hastie
Maximilian Schieck
Ashis K. Mondal
Marc Felde
Caspar I. van der Made
Janet S. Chou
Adrienne G. Randolph
Thomas Illig
Michael C. Zody
Catherine A. Brownstein
Alan H. Beggs
Alexander Hoischen
Alka Chaubey
Ravindra Kolhe
Source :
Biomolecules, Vol 13, Iss 1, p 133 (2023)
Publication Year :
2023
Publisher :
MDPI AG, 2023.

Abstract

Several studies have identified rare and common genetic variants associated with severe COVID-19, but no study has reported genetic determinants as predisposition factors for neurological complications. In this report, we identified rare/unique structural variants (SVs) implicated in neurological functions in two individuals with neurological manifestations of COVID-19. This report highlights the possible genetic link to the neurological symptoms with COVID-19 and calls for a collective effort to study these cohorts for a possible genetic linkage.

Details

Language :
English
ISSN :
2218273X
Volume :
13
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Biomolecules
Publication Type :
Academic Journal
Accession number :
edsdoj.95a26c6fc8714952844de03576ff847d
Document Type :
article
Full Text :
https://doi.org/10.3390/biom13010133