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Functional and metabolic alterations of gut microbiota in children with new-onset type 1 diabetes

Authors :
Xiaoxiao Yuan
Ruirui Wang
Bing Han
ChengJun Sun
Ruimin Chen
Haiyan Wei
Linqi Chen
Hongwei Du
Guimei Li
Yu Yang
Xiaojuan Chen
Lanwei Cui
Zhenran Xu
Junfen Fu
Jin Wu
Wei Gu
Zhihong Chen
Xin Fang
Hongxiu Yang
Zhe Su
Jing Wu
Qiuyue Li
Miaoying Zhang
Yufeng Zhou
Lei Zhang
Guang Ji
Feihong Luo
Source :
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

Here, by performing multi-omics microbiome analyses in a cohort of children with new-onset T1D, the authors characterize altered microbial functional and metabolic traits involved in T1D, which they validate in animal experiments, together providing potential avenues for microbiome-based interventions.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
13
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.95cd9add604a4672870058794889679b
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-022-33656-4