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Risk factors and predictive model for abdominal wound dehiscence in neonates: a retrospective cohort study

Authors :
Shouxing Duan
Xuan Zhang
Xuewu Jiang
Wenhui Ou
Maxian Fu
Kaihong Chen
Xinquan Xie
Wenfeng Xiao
Lian Zheng
Shuhua Ma
Jianhong Li
Source :
Annals of Medicine, Vol 53, Iss 1, Pp 900-907 (2021)
Publication Year :
2021
Publisher :
Taylor & Francis Group, 2021.

Abstract

AbstractBackground Abdominal wound dehiscence (AWD) is a major complication of abdominal surgery, and neonates are a group with a high risk of AWD, which has serious consequences or can even result in death. The purpose of this study is to explore the risk factors for neonatal AWD and construct a predictive model.Methods The clinical data of 453 cases that underwent neonatal laparotomy from June 2009 to June 2020 were retrospectively analyzed, among which 27 cases of AWD were identified. Nine factors, including gender, age at admission, weight at admission, preterm delivery, level of preoperative anaemia, hypoalbuminemia, operation time, incision length, and incision type, were analyzed to explore their correlation with neonatal AWD.Results The incidence of neonatal AWD was 6.0% (27/453), among which partial wound dehiscence accounted for 4.9% (22/453) and complete wound dehiscence accounted for 1.1% (5/453). Hypoproteinemia and incision type were the independent risk factors for neonatal AWD, and weight at admission was a protective factor for AWD in the multivariate models. All these factors were incorporated to construct a nomogram, and a calibration curve was plotted. The result indicated that the actual risk was close to the predicted risk when the predicted risk rate was greater than about 35%.Conclusions Neonatal AWD is closely related to hypoproteinemia and incision contamination. Our predictive model showed the potential to provide an individualized risk estimate of AWD for neonatal patients undergoing abdominal surgery.Key messagesNeonatal abdominal wound dehiscence (AWD) has a serious consequence and the incidence of neonatal AWD was about 6.0% and the complete AWD morbidity is 1.1%.Hypoproteinemia and incision type were the independent risk factors for neonatal AWD.Our predictive model showed the potential to provide an individualized risk estimate of AWD for neonatal patients undergoing abdominal surgery.

Details

Language :
English
ISSN :
07853890 and 13652060
Volume :
53
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Annals of Medicine
Publication Type :
Academic Journal
Accession number :
edsdoj.96069f26a100481e83bf0010518472d3
Document Type :
article
Full Text :
https://doi.org/10.1080/07853890.2021.1938661