Bronchogenic Carcinoma in a Scleroderma Patient with Multiple Metastases: One Case Report

The association between pulmonary interstitial fibrosis and the developmentof bronchogenic carcinoma in a patient with sclerodermahas been reported rarely[1]. It is hypothesized that intense epithelialproliferation that is accompanied by the fi brotic process increases theoccurrence of carcinomatous changes[2]. We report the case of a patientwho presented with 3-year history of Raynaud’s phenomenon,gradual tightening of the skin which was ignored by the patient andher family members, and a 2-week history of severe respiratory distresswith left shoulder and upper back pain followed by the developmentof paraparesis. After a series of examinations, the patient wasdiagnosed with scleroderma and simultaneously with bronchogeniccarcinoma and multiple distant metastases.