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Structural variants exhibit widespread allelic heterogeneity and shape variation in complex traits

Authors :
Mahul Chakraborty
J. J. Emerson
Stuart J. Macdonald
Anthony D. Long
Source :
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Publication Year :
2019
Publisher :
Nature Portfolio, 2019.

Abstract

Rare structural variants may account for a significant fraction of variation in complex traits. Here the authors analyse 14 Drosophila melanogaster genomes and find that structural variants are common, found in functionally important genes, and associated with QTLs.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
10
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.96ea71b67269422fb3fcaaf4399db70f
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-019-12884-1