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Maternal serum metabolome and traffic-related air pollution exposure in pregnancy
- Source :
- Environment International, Vol 130, Iss , Pp - (2019)
- Publication Year :
- 2019
- Publisher :
- Elsevier, 2019.
-
Abstract
- Background: Maternal exposure to traffic-related air pollution during pregnancy has been shown to increase the risk of adverse birth outcomes and neurodevelopmental disorders. By utilizing high-resolution metabolomics (HRM), we investigated perturbations of the maternal serum metabolome in response to traffic-related air pollution to identify biological mechanisms. Methods: We retrieved stored mid-pregnancy serum samples from 160 mothers who lived in the Central Valley of California known for high air particulate levels. We estimated prenatal traffic-related air pollution exposure (carbon monoxide, nitric oxides, and particulate matter
- Subjects :
- Environmental sciences
GE1-350
Subjects
Details
- Language :
- English
- ISSN :
- 01604120
- Volume :
- 130
- Issue :
- -
- Database :
- Directory of Open Access Journals
- Journal :
- Environment International
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.974515605a464235aafa9fc19428c383
- Document Type :
- article
- Full Text :
- https://doi.org/10.1016/j.envint.2019.05.066