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A Rare Case of Familial Neurogenic Diabetes Insipidus in a 22-Year-Old Man
- Source :
- AACE Clinical Case Reports, Vol 7, Iss 6, Pp 338-341 (2021)
- Publication Year :
- 2021
- Publisher :
- Elsevier, 2021.
-
Abstract
- Objective: Diabetes insipidus (DI) can be classified into 2 types: central/neurogenic DI and nephrogenic DI. Most cases of central DI occur after brain surgery, trauma, tumor, or infection. Here we report a rare case of familial central DI due to a heterozygous AVP gene mutation. Methods: A case of familial neurogenic DI has been described with thorough clinical, laboratory, and genetic workup. PubMed and Google scholar databases were used for literature discussion. Results: A 22-year-old man presented with polyuria and polydipsia. He drank about 4 gallons of water everyday and urinated large volumes very frequently. His physical examination was unremarkable. After 2 hours of water-deprivation, his serum sodium level was 147 mmol/L, serum osmolality was 302 mOsm/kg with concurrent urine osmolality of 78 mOsm/kg, vasopressin level was
Details
- Language :
- English
- ISSN :
- 23760605
- Volume :
- 7
- Issue :
- 6
- Database :
- Directory of Open Access Journals
- Journal :
- AACE Clinical Case Reports
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.97fcf741a46348a98e3b40d34ee5d073
- Document Type :
- article
- Full Text :
- https://doi.org/10.1016/j.aace.2020.11.031