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Bone mineral density in patients with juvenile idiopathic arthritis
- Source :
- Srpski Arhiv za Celokupno Lekarstvo, Vol 137, Iss 7-8, Pp 396-401 (2009)
- Publication Year :
- 2009
- Publisher :
- Serbian Medical Society, 2009.
-
Abstract
- Introduction. It is well known that juvenile idiopathic arthritis (JIA) as a chronic inflammatory disease with onset during the childhood, beside other complication, can lead to bone metabolism disturbance and osteoporosis. Objective. To assess bone mineral density (BMD) in children with JIA and to identify factors playing role in bone mineral disturbance. Methods. Seventy-five patients (26 male and 49 female) average disease duration 7.2 (2.4-16.8) years, and 73 age matched healthy control subjects (29 male and 44 female) participated in the study. Mean age of the groups was about 14.5 years. BMD was determined by dual x-ray absorptiometry (DEXA) of the lumbar spine (L2-L4). For further analysis we used the absolute value of BMD, expressed as g/cm2, Z score expressed as SD (relative value as standard deviation decline of normal BMD values of referent Italian population with identical age and gender), bone mineral content (BMC) as g/cm, and corrected BMD - BMDv as g/cm3. Results. Z score in the group of patients was significantly lower (-1.02±1.6) in comparison to the control group (-0.09±1.4; p
- Subjects :
- juvenile idiopathic arthritis
bone mineral density
Osteoporosis
Medicine
Subjects
Details
- Language :
- English, Serbian
- ISSN :
- 03708179
- Volume :
- 137
- Issue :
- 7-8
- Database :
- Directory of Open Access Journals
- Journal :
- Srpski Arhiv za Celokupno Lekarstvo
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.982e33e4b43b43e684a4f7efb86d2ccb
- Document Type :
- article
- Full Text :
- https://doi.org/10.2298/SARH0908396S