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The pharmacological mechanisms of omalizumab in patients with very high IgE levels—Clues from studies on atopic dermatitis

Authors :
Tse Wen Chang
Jiun-Bo Chen
Chia-Yu Chu
Source :
Dermatologica Sinica, Vol 30, Iss 4, Pp 147-153 (2012)
Publication Year :
2012
Publisher :
Wolters Kluwer Medknow Publications, 2012.

Abstract

Seventeen case series investigating the effects of omalizumab on patients with atopic dermatitis included patients whose pretreatment serum IgE was above 700 IU/ml, the upper inclusion limit specified in the product label. In all, 107 patients received omalizumab at doses of ≤375 mg every 2 weeks, which is recommended for patients with IgE

Details

Language :
English
ISSN :
10278117
Volume :
30
Issue :
4
Database :
Directory of Open Access Journals
Journal :
Dermatologica Sinica
Publication Type :
Academic Journal
Accession number :
edsdoj.987ea825a5d54423ae5e29e86a241273
Document Type :
article
Full Text :
https://doi.org/10.1016/j.dsi.2012.10.001