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Research Paper: Investigating the Effect of Environmental Temperature on the Phenomenon of Gene Transcription: Lyapunov Exponent

Authors :
Fatemeh Nemati
Sohrab Behnia
Source :
فیزیک کاربردی ایران, Vol 14, Iss 1, Pp 45-67 (2024)
Publication Year :
2024
Publisher :
Alzahra University, 2024.

Abstract

Gene expression is known as a phenomenon that shapes human life. This very complex phenomenon is formed from two stages: transcription and translation. In this study, we used the Nose-Hoover thermostat to model the effect of ambient temperature on gene expression since temperature regulates the biological clock of living systems. We have used the Lyapunov exponent approach to investigate the effect of control parameters on gene expression, including the degradation rates of messenger RNA and proteins, and to find critical points (phenomenon boundary limits), mRNA, and protein level boundary values. The rate of degradation in the process of protein synthesis has been investigated with the help of the Lyapunov exponent approach. According to this study, the optimal temperature for the production of mRNA molecules by Escherichia coli bacteria is 306 Kelvin. The study also used the chaos approach to show that the faster the mRNA molecules are degraded, the more they are transcribed, and the more chaotic the system becomes.

Details

Language :
Persian
ISSN :
27831043 and 27831051
Volume :
14
Issue :
1
Database :
Directory of Open Access Journals
Journal :
فیزیک کاربردی ایران
Publication Type :
Academic Journal
Accession number :
edsdoj.98d36e331f2f46b58be066a3e862ee2d
Document Type :
article
Full Text :
https://doi.org/10.22051/ijap.2023.44574.1340