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Of mitochondrion and COVID-19

Authors :
Khalid Omer Alfarouk
Sari T. S. Alhoufie
Abdelhameed Hifny
Laurent Schwartz
Ali S. Alqahtani
Samrein B. M. Ahmed
Ali M. Alqahtani
Saad S. Alqahtani
Abdel Khalig Muddathir
Heyam Ali
Adil H. H. Bashir
Muntaser E. Ibrahim
Maria Raffaella Greco
Rosa A. Cardone
Salvador Harguindey
Stephan Joel Reshkin
Source :
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1258-1266 (2021)
Publication Year :
2021
Publisher :
Taylor & Francis Group, 2021.

Abstract

COVID-19, a pandemic disease caused by a viral infection, is associated with a high mortality rate. Most of the signs and symptoms, e.g. cytokine storm, electrolytes imbalances, thromboembolism, etc., are related to mitochondrial dysfunction. Therefore, targeting mitochondrion will represent a more rational treatment of COVID-19. The current work outlines how COVID-19’s signs and symptoms are related to the mitochondrion. Proper understanding of the underlying causes might enhance the opportunity to treat COVID-19.

Details

Language :
English
ISSN :
14756366 and 14756374
Volume :
36
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Journal of Enzyme Inhibition and Medicinal Chemistry
Publication Type :
Academic Journal
Accession number :
edsdoj.993454466004434cb52a3371c266e824
Document Type :
article
Full Text :
https://doi.org/10.1080/14756366.2021.1937144