Back to Search
Start Over
Multi-Step Combined Upfront Surgery for Locally Advanced Paravertebral Sarcoma: A Case Report
- Source :
- Frontiers in Surgery, Vol 8 (2021)
- Publication Year :
- 2021
- Publisher :
- Frontiers Media S.A., 2021.
-
Abstract
- Background: Paravertebral localization of primary undifferentiated pleomorphic sarcoma (UPS) with bone and vascular involvement is infrequent and challenging. Multi-step surgical procedure has been described as a feasible and effective option to achieve sustained local tumor control.Methods: We report on a 62-year old man with paravertebral UPS infiltrating the aortic wall and the 9th thoracic vertebra who underwent a multi-step surgical procedure aimed at achieving oncologic radicality through a coordinated effort between thoracic, vascular and spinal surgeons. After balancing the risks and benefits of perioperative therapies, upfront surgery was performed including aortic resection with bypass grafting followed by a triple en bloc vertebrectomy with tumor excision. Mid-term follow-up (22 months) is then provided.Results: The combined procedure achieved oncological radicality and no local recurrence in the mid-term. No major complications occurred.Conclusions: Multi-step and multi-specialty surgery is a feasible and effective strategy to treat primary UPS in unfavorable localization. A strategic cooperation between surgeons and a multidisciplinary tumor board is required to define an optimal, personalized treatment strategy in sarcoma patients.
Details
- Language :
- English
- ISSN :
- 2296875X
- Volume :
- 8
- Database :
- Directory of Open Access Journals
- Journal :
- Frontiers in Surgery
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.99c67bf13e0045d98143b24fddd13228
- Document Type :
- article
- Full Text :
- https://doi.org/10.3389/fsurg.2021.664089