Elaboration of the Algorithm of MLST-Typing of Pandemic and Pre-Pandemic V. cholerae El Tor strains

Authors :: A. V. Ossin
Ya. M. Krasnov
N. P. Guseva
N. I. Smirnova
Source :: Проблемы особо опасных инфекций, Vol 0, Iss 1(107), Pp 58-61 (2011)
Publication Year :: 2011
Publisher :: Federal Government Health Institution, Russian Research Anti-Plague Institute “Microbe”, 2011.
Abstract: Molecular typing of pandemic and pre-pandemic cholera vibrio strains was carried out with the help of multi-locus sequence analysis. Application of two MLST schemes based on the sequence of virulence-associated and housekeeping genes demonstrated the last one to be the most effective in differentiation of strains, isolated before and during the seventh cholera pandemic.

Subjects :: vibrio cholerae
multi-locus sequence typing
virulence genes
housekeeping genes
Infectious and parasitic diseases
RC109-216

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