Back to Search
Start Over
Genetic determinants of risk in autoimmune pulmonary alveolar proteinosis
- Source :
- Nature Communications, Vol 12, Iss 1, Pp 1-6 (2021)
- Publication Year :
- 2021
- Publisher :
- Nature Portfolio, 2021.
-
Abstract
- Autoimmune pulmonary alveolar proteinosis (aPAP) is a complex lung disease caused by abnormal surfactant homeostasis. Here, the authors carry out a genome-wide association study of aPAP in a Japanese cohort, finding variants in the MHC and suggesting predisposition to abnormal antibody production.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 12
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.9a62f084a8e4179916af621aeb86739
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41467-021-21011-y