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Biointerfacial self-assembly generates lipid membrane coated bacteria for enhanced oral delivery and treatment

Authors :
Zhenping Cao
Xinyue Wang
Yan Pang
Shanshan Cheng
Jinyao Liu
Source :
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Publication Year :
2019
Publisher :
Nature Portfolio, 2019.

Abstract

Oral microbiota delivery is an approach to treat and prevent disease but suffers from low retention and bioavailability. Here the authors report on a lipid coating to protect against environmental assault maintaining viability and bioactivity of the bacteria and demonstrate effective application in a colitis model.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
10
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.9b1f08e6b5b442da8defad2bf3d2782c
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-019-13727-9