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Subcellular localization of hippocampal ryanodine receptor 2 and its role in neuronal excitability and memory

Authors :
Florian Hiess
Jinjing Yao
Zhenpeng Song
Bo Sun
Zizhen Zhang
Junting Huang
Lina Chen
Adam Institoris
John Paul Estillore
Ruiwu Wang
Henk E. D. J. ter Keurs
Peter K. Stys
Grant R. Gordon
Gerald W. Zamponi
Anutosh Ganguly
S. R. Wayne Chen
Source :
Communications Biology, Vol 5, Iss 1, Pp 1-16 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

A mouse model containing a GFP-tagged ryanodine receptor 2 (RyR2) has shed light on the precise subcellular localization of hippocampal RyR2 and mechanisms underlying neuronal excitability, learning, and memory.

Subjects

Subjects :
Biology (General)
QH301-705.5

Details

Language :
English
ISSN :
23993642
Volume :
5
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Communications Biology
Publication Type :
Academic Journal
Accession number :
edsdoj.9b9b91a266df4b92bd4d0f52c3d1dc44
Document Type :
article
Full Text :
https://doi.org/10.1038/s42003-022-03124-2