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Integrated extracellular microRNA profiling for ovarian cancer screening

Authors :
Akira Yokoi
Juntaro Matsuzaki
Yusuke Yamamoto
Yutaka Yoneoka
Kenta Takahashi
Hanako Shimizu
Takashi Uehara
Mitsuya Ishikawa
Shun-ichi Ikeda
Takumi Sonoda
Junpei Kawauchi
Satoko Takizawa
Yoshiaki Aoki
Shumpei Niida
Hiromi Sakamoto
Ken Kato
Tomoyasu Kato
Takahiro Ochiya
Source :
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Publication Year :
2018
Publisher :
Nature Portfolio, 2018.

Abstract

Screening methods for early detection of ovarian cancer is technically difficult. Here, the authors investigated circulating microRNA in human blood serum and developed a model using 10 microRNAs to discern between ovarian cancer and being ovarian tumors, solid tumors, and non-cancer patients.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
9
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.9ee9265b86e642b7b64def2709e6a9c9
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-018-06434-4