Neutrophil-to-Lymphocyte Ratio and Mean Platelet Volume in Chronic Otitis Media with or Without Cholesteatoma

Introduction: The neutrophil-to-lymphocyte ratio (NLR) can be used as a systemic inflammatory marker and the increased mean platelet volume (MPV) indicates that the inflammation is more intense. The aim of the study is to show the NLR and MPV values in chronic otitis media with or without ossicular/bony destruction or cholesteatoma and to investigate the predictive values of these parameters.Methods: Patients with chronic otitis media were retrospectively analyzed and divided into three groups: group 1 had only tympanic membrane perforation without any ossicular/bony erosion or cholesteatoma, group 2 had ossicular/bony erosion but no cholesteatoma, and group 3 had cholesteatoma. The control group (group 0) included subjects who were scheduled for septoplasty in our hospital, who did not have any otologic complaints, and who had normal otologic examination. Blood samples including complete blood count were obtained from all patients in their preoperative visit. The neutrophil, lymphocyte, platelet, and MPV values were obtained. NLR was calculated by dividing the number of neutrophils by the number of lymphocytes.Results: The study included 157 patients and 50 controls. There were 50 patients in groups 1 and 2 and 57 patients in group 3. The neutrophil, lymphocyte, NLR, MPV, and red blood cell distribution width values showed no statistically significant difference between the groups.Conclusion: Although NLR is related to the prognosis and severity of several diseases, we found no association between NLR, MPV and chronic ear disease. NLR and MPV also have no value in predicting prognosis and the accompanying ossicular or bony erosion accompanying COM.