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Ursolic acid benzaldehyde chalcone, leads to inhibition of cell proliferation and arrests cycle in G1/G0 phase in colon cancer
- Source :
- Saudi Journal of Biological Sciences, Vol 25, Iss 8, Pp 1762-1766 (2018)
- Publication Year :
- 2018
- Publisher :
- Elsevier, 2018.
-
Abstract
- The present study investigates the effect of matrine on colon cancer cell viability and apoptosis and tumor growth in mice xenograft model. The results from MTT assay revealed a concentration and time dependent reduction in viability of HCT8 and HT29 colon cancer cells by matrine. The viability of HCT8 and HT29 cells was reduced to 24.67 and 29.32% on treatment with 4 µM/ml concentration of matrine after 48 h (P
- Subjects :
- Biology (General)
QH301-705.5
Subjects
Details
- Language :
- English
- ISSN :
- 1319562X
- Volume :
- 25
- Issue :
- 8
- Database :
- Directory of Open Access Journals
- Journal :
- Saudi Journal of Biological Sciences
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.b14e34f7a3454a44bc8571d5de98631b
- Document Type :
- article
- Full Text :
- https://doi.org/10.1016/j.sjbs.2017.04.006