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Predictive Role of Fluorescein Angiography in Retinopathy of Prematurity

Authors :
Gianluca Dini
Alfredo Beccasio
Francesco Della Lena
Alberto Verrotti
Carlo Cagini
Source :
Pediatric Reports, Vol 16, Iss 3, Pp 594-601 (2024)
Publication Year :
2024
Publisher :
MDPI AG, 2024.

Abstract

Background: Fluorescein angiography (FA) has been a pivotal tool for studying the pathophysiology of retinopathy of prematurity (ROP) in vivo. We examined the course of ROP using FA to assess the predictive value of angiographic features. Methods: This is an observational retrospective cohort study of eyes screened for ROP with a binocular indirect ophthalmoscope and FA. RetCam fundus imaging and video digital fluorescein angiography were performed in the neonatal intensive care unit of Santa Maria Hospital of Perugia. The masked grading of the FA images was retrospectively conducted by two ROP expert ophthalmologists. Results: A total of 80 eyes of 40 patients were included for this study. Among the angiographic features evaluated, leakage, shunts, and tangles were predictive of the development of treatment-requiring ROP (p < 0.05). Conclusions: FA can add to our understanding of the evolution of vascular abnormalities in the course of ROP and can help predict which eyes will go on to treatment.

Details

Language :
English
ISSN :
20367503
Volume :
16
Issue :
3
Database :
Directory of Open Access Journals
Journal :
Pediatric Reports
Publication Type :
Academic Journal
Accession number :
edsdoj.b1b3b1a429f49e99ba71c09c08cfa8f
Document Type :
article
Full Text :
https://doi.org/10.3390/pediatric16030050