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Usefullnes of atherogenic indices and Ca-LDL level to predict subclinical atherosclerosis in patients with psoriatic arthritis?

Authors :
Duygu Tecer
Ismihan Sunar
Ali Erhan Ozdemirel
Rabia Tural
Orhan Kucuksahin
Aylin Sepici Dincel
Sebnem Ataman
Source :
Advances in Rheumatology, Vol 59, Iss 1, Pp 1-5 (2019)
Publication Year :
2019
Publisher :
BMC, 2019.

Abstract

Abstract Background To investigate the link between carbamylated low-density lipoprotein (ca-LDL), atherogenic index of plasma (AIP), atherogenic coefficient (AC), Castelli’s risk indices I and II (CRI I and II) and subclinic atherosclerosis in psoriatic arthritis (PsA). Methods Thirty-ninepatients and 19 age, sex, body mass index matched healthy controls were included. Insulin resistance (IR) was assessed with homeostasis of model assessment-IR (HOMA-IR). Carotid intima-media thickness (CIMT) was measured at both common carotid arteries and mean CIMT was calculated. Results The mean age was 49.50 ± 11.86 years and 64.1% were females in PsA group. In the PsA group, CIMT and HOMA-IR were significantly higher (p = 0.003, p = 0.043, respectively). AIP, AC, TG/HDL, CRI-1, CRI-2 and ca-LDL levels were similar between groups. In PsA group, CIMT was positively correlated with HOMA-IR, TG/HDL and AIP. Although ca-LDL was positively correlated with serum amyloid A (r = 0.744, p

Details

Language :
English
ISSN :
25233106
Volume :
59
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Advances in Rheumatology
Publication Type :
Academic Journal
Accession number :
edsdoj.b1ef257f3db64c42a52c77f247a52f52
Document Type :
article
Full Text :
https://doi.org/10.1186/s42358-019-0096-2