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Perturbing proteomes at single residue resolution using base editing

Authors :
Philippe C. Després
Alexandre K. Dubé
Motoaki Seki
Nozomu Yachie
Christian R. Landry
Source :
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Publication Year :
2020
Publisher :
Nature Portfolio, 2020.

Abstract

Base editors allow for the precise modification of genes. Here the authors use Target-AID to systematically test 17,000 sites across the yeast genome.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
11
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.b227619047ad4389a7f03d66669a8b2b
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-020-15796-7