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TECHNIQUE FOR THE ANALYSIS OF BIOINFORMATION DATA OF GENOMIC NATURE FOR THE DEVELOPMENT OF MULTIEPITOPE ANTICORONAVIRUS VACCINE MODELS

Authors :
Matvey V. Sprindzhuk
Aleksandr S. Vladyko
Zhuozhuang Lu
Leonid P. Titov
Vasiliy I. Bernik
Source :
Измерение, мониторинг, управление, контроль, Iss 3 (2023)
Publication Year :
2023
Publisher :
Penza State University Publishing House, 2023.

Abstract

Background. The coronavirus epidemic continues, but there is evidence that the society has already mastered effective measures for the prevention and treatment of this disease. The unresolved problems are prevention, early diagnosis and timely treatment of new viral epidemics, prevention and treatment of postcovid complications, the mortality from which manifests itself latently under the guise of other diseases and does not fall into the statistics of the coronavirus pandemic. Materials and methods. Based on the developed original data processing technique, designed for analyzing coronavirus genomic data, models of the anti-coronavirus multi-epitope vaccine were computed and tested in silico. In a series of computational experiments, evidence of their possible efficiency and safety was obtained. Results and conclusions. Based on research experiments and analysis of scientific literature, recommendations are formulated for the development and application of epitope antiviral vaccines using the example of the anti-coronavirus vaccine.

Details

Language :
English, Russian
ISSN :
23075538
Issue :
3
Database :
Directory of Open Access Journals
Journal :
Измерение, мониторинг, управление, контроль
Publication Type :
Academic Journal
Accession number :
edsdoj.b300e7b913549bea9559ef4c4909431
Document Type :
article
Full Text :
https://doi.org/10.21685/2307-5538-2023-3-6