The Relationship of Androgenic Alopecia and Opium Consumption in Men: A Comparative Study

Background: Androgenic alopecia (AGA) is one of the most common problems among men; in some societies, 50 percent of 50-years-old men are involved. In the past, opium versions of therapeutic compounds for the treatment of hair loss were used. Therefore, this study aimed to examine the relationship of opium consumption and androgenic alopecia in men. Methods: In this case-control study, 604 men referred to the Isfahan Amin Hospital, Iran, were enrolled. The sampling method was a simple classification (convenient) and men were divided to 2 equal groups of control (non-consumer of opium) and addict (consumer of opium). The intensity of androgenic alopecia was compared on the basis of a Hamilton Norwood scale. Data were collected using physical examination and a researcher-made questionnaire. Statistical analysis was carried using chi-square, Student's t, Spearman and One-way ANOVA tests. Findings: Percentage frequency of androgenic alopecia in addict men was significantly less than control group (P < 0.001). In addition, the intensity of androgenic alopecia had significant inverse relationship with the amount of opium consumption per year in the distinct range (P < 0.001). Conclusion: Our finding indicates that the prevalence of androgenic alopecia in opium-addict men is lower than non-consumer men.