Dynamics of proinflammatory cytokines level in stable angina (II–III functional class)

The article discusses the evaluation of cytokine level (IL-1β, IL-6) in patients with II–III functional class stable angina. In the group of patients with II–III class stable angina, the standard therapy failed to normalize the level of proinflammatory cytokines IL-1β and IL-6. In the group of patients with II–III class stable angina when the standard therapy combined with TES-therapy significantly reduced level of proinflammatory cytokines (IL-1β, IL6). TES-therapy decreases painful systemic inflammatory response more effectively than the standard therapy thus preventing damaging effect of proinflammatory cytokines. TES therapy produces a homeostatic effect, restores the balance of pro – and anti-inflammatory cytokines. We recommend to include TES-therapy in the standard treatment program in II–III class stable angina patients.