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Genomic heterogeneity of multiple synchronous lung cancer

Authors :
Yu Liu
Jianjun Zhang
Lin Li
Guangliang Yin
Jianhua Zhang
Shan Zheng
Hannah Cheung
Ning Wu
Ning Lu
Xizeng Mao
Longhai Yang
Jiexin Zhang
Li Zhang
Sahil Seth
Huang Chen
Xingzhi Song
Kan Liu
Yongqiang Xie
Lina Zhou
Chuanduo Zhao
Naijun Han
Wenting Chen
Susu Zhang
Longyun Chen
Wenjun Cai
Miaozhong Shen
Ningzhi Xu
Shujun Cheng
Huanming Yang
J. Jack Lee
Arlene Correa
Junya Fujimoto
Carmen Behrens
Chi-Wan Chow
William N. William
John V. Heymach
Waun Ki Hong
Stephen Swisher
Ignacio I. Wistuba
Jun Wang
Dongmei Lin
Xiangyang Liu
P. Andrew Futreal
Yanning Gao
Source :
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
Publication Year :
2016
Publisher :
Nature Portfolio, 2016.

Abstract

Some patients present with multiple lung tumours but it is unclear whether these are metastases or individual lesions. Here, the authors use genomics techniques to demonstrate in six patients that multiple tumours have individual genetic profiles and represent separate tumours.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723 and 32046278
Volume :
7
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.b47899a5b32046278f07cf214de45ffc
Document Type :
article
Full Text :
https://doi.org/10.1038/ncomms13200