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Assessment of Cognitive Function in Romanian Patients with Chronic Alcohol Consumption

Authors :
Shandiz Morega
Claudiu-Marinel Ionele
Mihaela-Andreea Podeanu
Dan-Nicolae Florescu
Ion Rogoveanu
Source :
Gastroenterology Insights, Vol 15, Iss 2, Pp 433-446 (2024)
Publication Year :
2024
Publisher :
MDPI AG, 2024.

Abstract

Alcoholism presents a significant health concern with notable socioeconomic implications. Alcohol withdrawal syndrome (AWS) can manifest when individuals cease or drastically reduce their alcohol consumption after prolonged use. Non-alcoholic fatty liver disease (NAFLD) is characterized by substantial lipid accumulation in the liver cells of individuals with no history of alcohol consumption. There is evidence suggesting an association between cognitive impairment and both conditions. This study aimed to evaluate cognitive impairment in patients with NAFLD and AWS using the Mini-Mental State Examination (MMSE). This study involved 120 patients admitted to two hospitals in Craiova, Romania. Results indicated that patients with NAFLD did not exhibit cognitive impairment as measured by MMSE (Mean = 29.27, SD = 0.785). Conversely, patients with AWS showed more pronounced cognitive dysfunction, with a mean MMSE score at admission of 16.60 ± 4.097 and 24.60 ± 2.832 after 2 weeks under treatment with Vitamins B1 and B6 and Cerebrolysin. Additionally, our findings suggested that cognitive dysfunction among alcohol consumers was correlated with the severity of clinical symptoms, as demonstrated by the severity of tremors in our study. The two-week period under treatment and alcohol withdrawal was insufficient for cognitive function to return to normal levels. Observational studies on longer periods of time are advised.

Details

Language :
English
ISSN :
20367422 and 20367414
Volume :
15
Issue :
2
Database :
Directory of Open Access Journals
Journal :
Gastroenterology Insights
Publication Type :
Academic Journal
Accession number :
edsdoj.b812e88fb4354e8c86f4929fe2c6057a
Document Type :
article
Full Text :
https://doi.org/10.3390/gastroent15020031