Spontaneous resorption of an infantile mandibular myofibroma case report

AbstractMyofibroma of the mandible is a rare, benign neoplasm with current treatment consisting of surgical excision. Various approaches have been reported from enucleation or curettage to segmental mandibulectomy and free tissue transfer techniques. There are no reports in the literature of observation for spontaneous regression. An 11-month-old female was diagnosed with mandibular myofibroma. During workup of the mass, interval imaging demonstrated a decrease in size of the lesion. To avoid an extensive surgical resection, observation and repeat imaging was recommended to the patient’s family. Given ongoing decrease in the size of the lesion and its asymptomatic nature, the patient has continued to be observed clinically and radiographically. This is the first report of mandibular myofibroma managed with observation wherein there seems to have been spontaneous regression of the mass without any intervention.