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Anticancer Potential of Resveratrol, β-Lapachone and Their Analogues

Authors :
Danielly C. Ferraz da Costa
Luciana Pereira Rangel
Mafalda Maria Duarte da Cunha Martins-Dinis
Giulia Diniz da Silva Ferretti
Vitor F. Ferreira
Jerson L. Silva
Source :
Molecules, Vol 25, Iss 4, p 893 (2020)
Publication Year :
2020
Publisher :
MDPI AG, 2020.

Abstract

This review aims to explore the potential of resveratrol, a polyphenol stilbene, and beta-lapachone, a naphthoquinone, as well as their derivatives, in the development of new drug candidates for cancer. A brief history of these compounds is reviewed along with their potential effects and mechanisms of action and the most recent attempts to improve their bioavailability and potency against different types of cancer.

Details

Language :
English
ISSN :
14203049
Volume :
25
Issue :
4
Database :
Directory of Open Access Journals
Journal :
Molecules
Publication Type :
Academic Journal
Accession number :
edsdoj.b83b2b4597416e81eb5a8087335a32
Document Type :
article
Full Text :
https://doi.org/10.3390/molecules25040893