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Association between diverticular disease and colorectal cancer: a bidirectional mendelian randomization study

Authors :
Yanxi Zhang
Han Zhang
Jinghan Zhu
Yazhou He
Peng Wang
Doudou Li
Xiaozhuan Liu
Wen Jin
Junxi Zhang
Chuan Xu
Zengli Yu
Xin Zhao
Lingling Cui
Source :
BMC Cancer, Vol 23, Iss 1, Pp 1-8 (2023)
Publication Year :
2023
Publisher :
BMC, 2023.

Abstract

Abstract Background: Diverticular disease has been inconsistently associated with colorectal cancer risk. We conducted a bidirectional Mendelian randomization study to assess this association. Methods: Forty-three and seventy single-nucleotide polymorphisms associated with diverticular disease and colorectal cancer at the genome-wide significance level (p

Details

Language :
English
ISSN :
14712407
Volume :
23
Issue :
1
Database :
Directory of Open Access Journals
Journal :
BMC Cancer
Publication Type :
Academic Journal
Accession number :
edsdoj.b8446b3d74944c65abe30b4cc6fd5f22
Document Type :
article
Full Text :
https://doi.org/10.1186/s12885-023-10606-x