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Current understanding of the rational diagnostics and treatment of acquired myasthenia gravis. Part 2: treatment

Authors :
S. N. Bardakov
S. A. Zhivolupov
E. R. Barantsevich
M. V. Zakharov
I. N. Samartsev
Source :
Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, Vol 23, Iss 3, Pp 6-11 (2016)
Publication Year :
2016
Publisher :
Academician I.P. Pavlov First St. Petersburg State Medical University, 2016.

Abstract

Due to the fact that acquired myasthenia gravis is an autoimmune disease, so rational treatment of these patients includes the symptomatic therapy (acetylcholinesterase inhibitors, potassium supplements, potassiumsaving diuretics), short-term immunotherapy (intravenous immunoglobulin, methods of extracorporeal hemocorrection), longterm immunotherapy (glucocorticosteroids, cytotoxic agents, targeted therapies), thymectomy, as well as a number of new promising therapeutic agents. The choice of effective therapy depends on identifying the clinical forms of myasthenia gravis and a complete analysis of autoimmune mechanisms underlying the disease because of similar clinical forms of myasthenia gravis may respond to similar therapies.

Details

Language :
Russian
ISSN :
16074181 and 25418807
Volume :
23
Issue :
3
Database :
Directory of Open Access Journals
Journal :
Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова
Publication Type :
Academic Journal
Accession number :
edsdoj.b85764c0dbe94e9584c2c87487709d29
Document Type :
article
Full Text :
https://doi.org/10.24884/1607-4181-2016-23-3-6-11