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Relationship between PMN-endothelium interactions, ROS production and Beclin-1 in type 2 diabetes

Authors :
Aranzazu M. De Marañon
Francesca Iannantuoni
Zaida Abad-Jiménez
Francisco Canet
Pedro Díaz-Pozo
Sandra López-Domènech
Ana Jover
Carlos Morillas
Guillermo Mariño
Nadezda Apostolova
Milagros Rocha
Victor M. Victor
Source :
Redox Biology, Vol 34, Iss , Pp 101563- (2020)
Publication Year :
2020
Publisher :
Elsevier, 2020.

Abstract

Type 2 diabetes is closely related to oxidative stress and cardiovascular diseases. In this study, we hypothesized that polymorphonuclear leukocytes (PMN)-endothelium interactions and autophagy are associated. We evaluated PMN-endothelial interactions, ROS production and autophagy parameters in 47 type 2 diabetic patients and 57 control subjects. PMNs from type 2 diabetic patients exhibited slower rolling velocity (p

Details

Language :
English
ISSN :
22132317
Volume :
34
Issue :
101563-
Database :
Directory of Open Access Journals
Journal :
Redox Biology
Publication Type :
Academic Journal
Accession number :
edsdoj.b8b76d46474b4599b2589bd0b780d0e9
Document Type :
article
Full Text :
https://doi.org/10.1016/j.redox.2020.101563