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A pediatric brain tumor atlas of genes deregulated by somatic genomic rearrangement

Authors :
Yiqun Zhang
Fengju Chen
Lawrence A. Donehower
Michael E. Scheurer
Chad J. Creighton
Source :
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Publication Year :
2021
Publisher :
Nature Portfolio, 2021.

Abstract

The global impact of somatic structural variants (SSVs) on gene expression in childhood cancers is unclear. Here, the authors analyse cancer genome and RNA sequencing data of 854 pediatric brain tumours and report a landscape of genes deregulated by SSVs.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
12
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.b8ca0e9586749df99643f4d66cc5fc9
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-021-21081-y