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Multilevel proteomic analyses reveal molecular diversity between diffuse-type and intestinal-type gastric cancer

Authors :
Wenhao Shi
Yushen Wang
Chen Xu
Yan Li
Sai Ge
Bin Bai
Kecheng Zhang
Yunzhi Wang
Nairen Zheng
Juan Wang
Shiqi Wang
Gang Ji
Jipeng Li
Yongzhan Nie
Wenquan Liang
Xiaosong Wu
Jianxin Cui
Yi Wang
Lin Chen
Qingchuan Zhao
Lin Shen
Fuchu He
Jun Qin
Chen Ding
Source :
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Publication Year :
2023
Publisher :
Nature Portfolio, 2023.

Abstract

The molecular differences between the two major gastric cancer subtypes diffuse-type gastric cancer (DGC) and intestinaltype gastric cancer (IGC) remain to be investigated. Here, integrated analysis of proteome, phospho-proteome and transcription factor activity for DGC and IGC reveals potential subtypes.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
14
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.b8d7e9eefad24deeb27fe648beb9743f
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-023-35797-6