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The Effect of Deuteration and Homologation of the Lactam Ring of Nirmatrelvir on Its Biochemical Properties and Oxidative Metabolism

Authors :
Elena Arutyunova
Alexandr Belovodskiy
Pu Chen
Muhammad Bashir Khan
Michael Joyce
Holly Saffran
Jimmy Lu
Zoe Turner
Bing Bai
Tess Lamer
Howard S. Young
John C. Vederas
D. Lorne Tyrrell
M. Joanne Lemieux
James A. Nieman
Source :
ACS Bio & Med Chem Au, Vol 3, Iss 6, Pp 528-541 (2023)
Publication Year :
2023
Publisher :
American Chemical Society, 2023.

Details

Language :
English
ISSN :
26942437
Volume :
3
Issue :
6
Database :
Directory of Open Access Journals
Journal :
ACS Bio & Med Chem Au
Publication Type :
Academic Journal
Accession number :
edsdoj.b8e37dea5f004761a5ac48cc97ba66e2
Document Type :
article
Full Text :
https://doi.org/10.1021/acsbiomedchemau.3c00039